Medical Definition of Catechol o-methyltransferase
1.
An enzyme of the transferase class that catalyses the transfer of a methyl group from s-adenosylmethionine to a catechol or catecholamine such as dopa, dopamine, norepinephrine, or epinephrine. (converting to normetanephrine and metanephrine, respectively), the methyl group coming from S-adenosyl-l-methionine. An important step in the catabolism of the catecholamines.
The enzyme occurs in the cytoplasm, particularly in the kidney, liver, and central nervous system.
Chemical name: S-Adenosyl-L-methionine:catechol O-methyltransferase
Registry number: EC 2.1.1.6
(05 May 2002)
Lexicographical Neighbors of Catechol O-methyltransferase
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