Medical Definition of Carbamoyl phosphate synthetase

1. A phosphotransferase catalyzing the formation of carbamoyl phosphate. There are two significant isozymes. Carbomoyl phosphate synthetase I is a mitochondrial enzyme that catalyses the reaction of 2ATP, NH3, CO2, and H2O to carbamoyl phosphate, 2ADP, and Pi. It is activated by N-acetylglutamate and participates in urea biosynthesis. A deficiency of carbamoyl phosphate synthetase I can result in hyperammonaemia. Carbamoyl phosphate synthetase II is a cytosolic enzyme that, under physiological conditions, uses l-glutamine as the nitrogen source (producing l-glutamate) instead of NH3, is not activated by N-acetylglutamate, and is found in pyrimidine biosynthesis. (05 Mar 2000)

Lexicographical Neighbors of Carbamoyl Phosphate Synthetase

carbamic acid
carbamide
carbamides
carbamidomethyl
carbamidomethylation
carbamine
carbamines
carbamino
carbamino compound
carbaminohemoglobin
carbamoate
carbamoyl
carbamoyl-phosphate synthase (ammonia)
carbamoyl-phosphate synthase (glutamine-hydrolyzing)
carbamoyl phosphate
carbamoyl phosphate synthetase (current term)
carbamoylaspartate dehydrase
carbamoylation
carbamoylcarbamic acid
carbamoylphosphate synthetase deficiency
carbamoyls
carbamoyltransferase
carbamoylurea
carbamyl
carbamyl phosphate
carbamylation
carbamylcholine
carbamylcholine chloride
carbamyls
carbane

Other Resources:

Search for Carbamoyl phosphate synthetase on Dictionary.com!Search for Carbamoyl phosphate synthetase on Thesaurus.com!Search for Carbamoyl phosphate synthetase on Google!Search for Carbamoyl phosphate synthetase on Wikipedia!

Search