Definition of Calpain
1. an enzyme for digesting proteins [n -S]
Medical Definition of Calpain
1.
Calcium activated cytoplasmic proteases containing the EF hand motif. Calpain I is activated by micromolar calcium, Calpain II by millimolar calcium.
Calpain has two subunits, the larger (80 kD) has 4 domains one homologous with papain, one with calmodulin, the smaller (30 kD) has one domain homologous with calmodulin. First isolated from erythrocytes, but now described from other cells.
(13 Oct 1997)
Lexicographical Neighbors of Calpain
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