Medical Definition of Cafe-au-lait spot
1.
A pigmented cutaneous lesion, that can range from light to dark brown, and is due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes.
Café-au-lait spots are one of the major skin manifestations of neurofibromatosis (von Recklinghausen disease) with type 1 (peripheral) neurofibromatosis, almost always 6 or more cafe-au-lait spots can be found with at least some exceeding 1.5 cm in diameter. These are often accompanied by freckle-like spots in the axilla.
(05 May 2002)
Lexicographical Neighbors of Cafe-au-lait Spot
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