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Medical Definition of Bone marrow purging
1. Techniques for the removal of subpopulations of cells (usually residual tumour cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic bone marrow transplantation. (12 Dec 1998)