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Definition of Biglycan
1. Noun. (protein) A small leucine-rich repeat proteoglycan which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon ¹
¹ Source: wiktionary.com
Medical Definition of Biglycan
1. A small proteoglycan, 150-240 kD, of the extracellular matrix. The core protein has a mass of _42 kD and is very similar to the core protein of decorin and fibromodulin. All three have highly conserved sequences containing 10 internal homologous repeats of _ 25 amino acids with leucine rich motifs. Biglycan has two glycosaminoglycan chains, either chondroitin sulphate or dermatan sulphate and N linked oligosaccharides. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)