Medical Definition of Base analogue
1.
A chemical which resembles a nucleotide base. They can substitute the Purine and pyrimidine bases that normally appear in DNA, despite minor differences in structure. May be used for inducing mutations, including point mutations.
For example: 5 bromouracil can replace thymine or 2 aminopurine replace adenine.
(13 Nov 1997)
Lexicographical Neighbors of Base Analogue
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