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Definition of Ball of the thumb
1. Noun. (anatomy informal) The fleshy portion, opposite the nail, of the first segment (first phalange) of the human thumb. ¹
2. Noun. (anatomy) The most fleshy portion of the palm of the human hand, located adjacent to the second joint of the thumb: the thenar eminence. ¹
¹ Source: wiktionary.com