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Medical Definition of Apolipoproteins c
1. Lipoproteins located on the surface of vldl. They are transferred to hdl throughout the catabolism of vldl and affect lipoprotein lipase activity. A genetic lack of apo c-II results in hyperglyceridemia and low levels of hdl. Another form of hyperglyceridemia with normal apo c-II levels is caused by a high concentration of apo c-III in vldl. (12 Dec 1998)