Medical Definition of Aphidicolin

1. Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol. An antiviral antibiotic produced by cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells. Pharmacological action: antiviral agents, enzyme inhibitors. Chemical name: 9,15-Cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3alpha,4alpha,5alpha,17alpha)- (12 Dec 1998)

Lexicographical Neighbors of Aphidicolin

aphetically
aphetise
aphetised
aphetises
aphetize
aphetized
aphetizes
aphicide
aphicides
aphid
aphid
aphides
aphidian
aphidian
aphidians
aphidicolin (current term)
Aphididae
aphidivorous
Aphidoidea
aphidophagous
aphids
aphid lion
aphilopony
aphis
Aphis
Aphis fabae
aphis lion
aphis lion
Aphis pomi
apholate

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