Lexic.us

Definition of Antimetabolite

1. Noun. An antineoplastic drug that inhibits the utilization of a metabolite.

Definition of Antimetabolite

1. Noun. (medicine) Any substance that competes with, or inhibits the normal metabolic process, often by acting as an analogue of an essential metabolite ¹

¹ Source: wiktionary.com

Definition of Antimetabolite

1. [n -S]

Medical Definition of Antimetabolite

1. A group of anti-cancer drugs which prevent cells growing and dividing by blocking the chemical reactions required in the dividing by blocking the chemical reactions required in the cell to produce DNA. Drugs of this type include 6 mercaptopurine, azathioprine, thioguanine, methotrexate. See: chemotherapy. (13 Oct 1997)

Lexicographical Neighbors of Antimetabolite

Literary usage of Antimetabolite

Below you will find example usage of this term as found in modern and/or classical literature:

1. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"... the description of cadmium as an antimetabolite of zinc (17). If the diet contains inadequate amounts of zinc, toxicity from cadmium exposure can be ..."

2. Getting Fit Your Way: A Self-paced Fitness Guide (1993)
"Mechanism of Action and Use Drugs like azathioprine, methotrexate, and cyclosporine are referred to as antimetabolite agents. These drugs block metabolic ..."

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