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Medical Definition of Anisochromasia
1. The unequal distribution of haemoglobin in the red blood cells, such that the periphery is pigmented and the central region is virtually colourless, as observed in films of blood from persons with certain forms of anaemia caused by deficiency of iron; normal red blood cells show mild anisochromasia because of their biconcave shape. Origin: aniso-+ G. Chroma, colour (05 Mar 2000)