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Medical Definition of Angioimmunoblastic lymphadenopathy with dysproteinaemia
1. A lymphoproliferative disorder characterised by generalised lymphadenopathy, hepatosplenomegaly, fever, sweats, weight loss, skin lesions, and pruritus with hypergammaglobulinaemia; occurs primarily in older adults, often with fatal outcome. Proliferation of B-cells, deficiency of T-cells has been demonstrated. Synonym: immunoblastic lymphadenopathy. (05 Mar 2000)