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Definition of And-
1. Prefix. (no longer productive) A prefix of Old English origin meaning "against", "back", "in return", "away", represented in Modern English by ''a-'', ''an-'', ''on-'', and in altered form by the reverse-action prefix (term un-) (i.e. (term unbuckle)). Also as the initial letter ''d'' in (term dread) (< Old English (term ondrædan ondr?dan lang=ang)). ¹
¹ Source: wiktionary.com