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Medical Definition of Ampullary crest
1. An elevation on the inner surface of the ampulla of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass. Synonym: crista ampullaris, acoustic crest, transverse septum. (05 Mar 2000)