Lexic.us

Definition of Alcaptonuria

1. Noun. A rare recessive metabolic anomaly marked by ochronosis and the presence of alkapton in the urine.

Definition of Alcaptonuria

1. Noun. (alternative spelling of alkaptonuria) ¹

¹ Source: wiktionary.com

Medical Definition of Alcaptonuria

1. The excretion of homogentisic acid (alkapton) in the urine due to the congenital absence of the enzyme homogentisate 1,2-dioxygenase. This enzyme mediates the breakdown of the amino acids phenylalanine and tyrosine. The urine may be quite dark, particularly when allowed to stand. Origin: Gr. Ouron = urine (27 Sep 1997)

Lexicographical Neighbors of Alcaptonuria

Literary usage of Alcaptonuria

Below you will find example usage of this term as found in modern and/or classical literature:

1. Pathological physiology of internal diseases by Albion Walter Hewlett (1916)
"These latter have been discussed more fully in the paragraphs on intestinal auto-intoxication. alcaptonuria ..."

2. A Text-book of Physiological Chemistry by Olof Hammarsten, Sven Gustaf Hedin (1914)
"DAKIN therefore considers alcaptonuria as a condition in which partly the formation of an abnormal metabolic product—the homogentisic acid—takes place and ..."

3. A Textbook of physiological chemistry by Olof Hammarsten (1906)
"On the ingestion of tyrosin by persons with alcaptonuria, WOLKOW and BAUMANN ... According to LANGSTEIN and FALTA alcaptonuria seems to be an anomaly of the ..."

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