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Medical Definition of Acute febrile neutrophilic dermatosis
1. A rare dermatosis, predominant in women, of rapid onset and characterised by plaque-like lesions, usually multiple, on the face, neck, and upper extremities, accompanied by conjunctivitis, mucosal lesions, fever, malaise, arthralgia, and peripheral blood neutrophilia in many cases; biopsy reveals polymorphonuclear infiltrate of the dermis; rapid remission occurs with systemic steroid therapy. Synonym: Sweet's disease. (05 Mar 2000)