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Definition of Acantholysis
1. Noun. A breakdown of a cell layer in the epidermis (as in pemphigus).
Definition of Acantholysis
1. Noun. (medicine) The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. ¹
¹ Source: wiktionary.com
Medical Definition of Acantholysis
1. Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris and keratosis follicularis. (12 Dec 1998)