Lexic.us

Definition of Zollinger-Ellison syndrome

1. Noun. Syndrome consisting of intractable peptic ulceration with gastric hypersecretion and hyperacidity.

Definition of Zollinger-Ellison syndrome

1. Noun. (medicine) A disorder where increased levels of the hormone gastrin are produced, causing the stomach to produce excess hydrochloric acid; often caused by a tumor (gastrinoma) of the duodenum or pancreas, and resulting in peptic ulcers. ¹

¹ Source: wiktionary.com

Medical Definition of Zollinger-Ellison syndrome

1. A tumour (gastrinoma) of the pancreatic islet cells that results in an over production of gastric acid, leading to fulminant ulceration of the oesophagus, stomach, duodenum and jejunum. Gastrinomas may also occur in the stomach, duodenum, spleen and regional lymph nodes. Treatment includes the use of H2 antagonists (for example cimetidine, ranitidine). Surgical excision of the tumour is curative in approximately 25% of patients. (27 Sep 1997)

Lexicographical Neighbors of Zollinger-Ellison Syndrome

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