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Medical Definition of UMP synthase
1. Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5'-monophosphate; 2' and 3' derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. Synonym: UMP synthase, uridine 5'-monophosphate. Uridylic acid synthase, a bifunctional enzyme that contains the activities of both orotate phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase; catalyses a key step in pyrimidine biosynthesis; a deficiency of this enzyme leads to orotic aciduria. (05 Mar 2000)
Lexicographical Neighbors of UMP Synthase
ULDUSTA ULF ULIRG ULIRGs ULOC ULRR ULSI UM UMA UMB | UMC UML UMLS UMOC UMP UMP synthase (current term) UMTS UN UN*X UNA | UNAMIR UNAs UNC UNCK WT UNCLO UNDG UNDM UNEP UNESCO UNICEF |