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Medical Definition of Treponema pallidum immobilization test
1. A test for syphilis in which an antibody other than Wassermann antibody is present in the serum of a syphilitic patient, which in the presence of complement causes the immobilization of actively motile Treponema pallidum obtained from testes of a rabbit infected with syphilis. Synonym: TPI test, Treponema pallidum immobilization reaction. (05 Mar 2000)