Definition of TNF

1. Noun. A proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis).

Exact synonyms: Tumor Necrosis Factor, Tumour Necrosis Factor
Generic synonyms: Cytokine

Definition of TNF

1. Initialism. (medicine) Tumour Necrosis Factor. ¹

¹ Source: wiktionary.com

Medical Definition of TNF

1. Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997)

Lexicographical Neighbors of TNF

TM-mode
TMA
TMD
TMI
TMJ
TMJD
TMP
TMP-SMX
TMR
TMS
TMT
TMTOWTDI
TMV
TN
TNA
TNF (current term)
TNF-IL1-activated protein kinase
TNG
TNLN
TNM
TNM staging
TNN
TNO
TNOs
TNR
TNT
TO
TOC
TOCP

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