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Medical Definition of Shine Dalgarno region
1. A poly purine sequence found in bacterial mRNA about 7 nucleotides in front of the initiation codon, AUG. The complete sequence is 5' AGGAGG 3' and almost all messengers contain at least half of this sequence. It is complementary to a highly conserved sequence at the 3' end of 16s ribosomal RNA, 3' UCCUCC 5' and it is thought to be involved in the binding of the mRNA to the ribosome. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Shine Dalgarno Region
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