Medical Definition of Nissl granule
1.
| Discrete clumps of material seen by phase contrast microscopy in the perikaryon of some neurons, particularly motor neurons.
They are basophilic and contain much RNA, are actually regions very rich in rough endoplasmic reticulum. Their reaction following damage to neurons is characteristic, they disperse through the cytoplasm giving a general basophilia to the whole cell body.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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Lexicographical Neighbors of Nissl Granule
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