Medical Definition of NAD(p)h dehydrogenase (quinone)
1.
A flavoprotein that reversibly catalyses the oxidation of NADH or NADPH by various quinones and oxidation-reduction dyes. Since the enzyme is a part of the mitochondrial respiratory chain, defects or deficiencies of this enzyme are an important cause of neurological diseases such as parkinsonism. It may have a protective effect against cancer caused by quinones or their metabolic precursors. The enzyme is inhibited by dicoumarol, capsaicin, and caffeine.
Chemical name: NAD(P)H:(quinone-acceptor) oxidoreductase
Registry number: EC 1.6.99.2
(12 Dec 1998)
Lexicographical Neighbors of NAD(p)h Dehydrogenase (quinone)
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