2. Noun. (neurotoxin) A byproduct of synthetic heroin, or MPPP, which causes Parkinsonian symptoms in users. ¹
3. Noun. (neurotoxin) A neurotoxin which degrades into MPP+ after crossing the blood brain barrier, which causes a degredation of the dopaminergic neurons within the substantia nigra. ¹
¹ Source: wiktionary.com
Medical Definition of MPTP
1. N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine;piperidine derivative which causes irreversible symptoms of parkinsonism in humans and monkeys. A by-product of illicitly manufactured meperidine that caused numerous cases of parkinsonism. Used as an experimental tool in research on parkinsonism. (05 Mar 2000)
Lexicographical Neighbors of MPTP
| MPEG MPEGs MPG MPH MPKC MPMD MPO MPP MPPG MPPP | MPPs MPS MPT MPTP (current term) MPV MP joints MQSA MR MR/DD MRA | MRAM MRAP MRB MRBM MRC MRCA MRCC MRCGP |
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