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Medical Definition of Holmes heart
1. A variant of double inlet left ventricle where the ventricular-arterial connection is concordant and the right ventricle is rudimentary. Horizontal heart, description of the heart's electrical position; recognised in the electrocardiogram when the QRS in lead aVL resembles that in V6 and QRS in aVF resembles that in V1; also, loosely, when the electrical axis lies between -30° and +30°. (05 Mar 2000)