¹ Source: wiktionary.com
Medical Definition of GLP
1. A keto derivative of proline that is formed nonenzymatically from glutamate, glutamine, and gamma-glutamylated peptides; it is also produced by the action of gamma-glutamylcyclotransferase; elevated levels of 5-oxoproline are often associated with problems of glutamine or glutathione metabolism. Synonym: 5-pyrrolidone-2-carboxylic acid, pyroglutamic acid, pyrrolidone-5-carboxylate. (05 Mar 2000)