Medical Definition of ANK repeat
1.
Amino acid motif found in diverse proteins including ankyrins (hence the name), the notch product, transcriptional regulators, cell cycle regulatory proteins and a toxin produced by the black widow spider.
The motif is about 33 amino acids long and is generally found as a tandem array of 2-7 repeats, though ankyrins contain 24 repeats. Their role is not established, but they may be involved in protein protein binding.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(22 Feb 2008)
Lexicographical Neighbors of ANK Repeat
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