Medical Definition of Tumour suppressor

1. A gene that encodes a product that normally negatively regulates the cell cycle and that must be mutated or otherwise inactivated before a cell can proceed to rapid division. Examples: p53, RB retinoblastoma), WT 1 (Wilm's tumour), DCC (deleted in colonic carcinoma), NF 1 (neurofibrosarcoma) and APC adenomatous polyposis coli). This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)



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Lexicographical Neighbors of Tumour Suppressor

tumour debulking
tumour embolism
tumour escape
tumour initiation
tumour lysis syndrome
tumour marker
tumour necrosis factor
tumour necrosis factor-beta
tumour progression
tumour promoter
tumour registry
tumour specific antigen
tumour stage
tumour stem cells
tumour suppressor (current term)
tumour virus
tumour virus infections
tumouraffin
tumoural calcinosis
tumoured
tumouricidal
tumourigeneses
tumourigenesis
tumourigenic
tumourigenicity
tumourless
tumourlets
tumourlike
tumourous

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