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Medical Definition of Tocotrienol
1. A tocol with three double bonds in the side chain, i.e., with three additional double bonds in the phytyl chain, thus a 6-(3',7',11',15'-tetramethyl-2',6',10',14'-hexadecatetraenyl)-1,4-hydroquinone or a 2-methyl-2-(4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-ol. The natural products carry methyls at one or more of positions 5, 7, and 8 of the chromanol and are thus identical, except for the unsaturation in the phytyl-like side chain, to the tocopherols; also analogous is the cyclization to form a chromanol derivative and oxidation to form the tocotrienolquinones (or chromenols). Abbreviated T-n (hydroquinone form) or TQ-n (quinone form) and preceded by alpha-, beta-, etc., as in the tocopherols, to indicate degree of methylation (the n indicates the number of intact isoprene or prenyl units remaining in the chromanol or chromenol form). Tocotrienol terminology is used to indicate relationships to tocols and tocoenols (vitamin E-like), the chromanol terminology to indicate relationship to the isoprenoidal compounds of the vitamin K and coenzyme Q series. (05 Mar 2000)
Lexicographical Neighbors of Tocotrienol
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