Definition of Tacrine

1. Noun. A parasympathomimetic anticholinesterase, one of the first approved for the treatment of Alzheimer's disease. ¹

¹ Source: wiktionary.com

Definition of Tacrine

1. a drug for treating Alzheimer's disease [n -S]

Medical Definition of Tacrine

1. A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of alzheimer's disease and other central nervous system disorders. Pharmacological action: cholinesterase inhibitor, nootropic agents, parasympathomimetic. Chemical name: 9-Acridinamine, 1,2,3,4-tetrahydro- (12 Dec 1998)

Lexicographical Neighbors of Tacrine

tacks up
tacksman
tacksmen
tacky
tacnode
tacnodes
taco salad
taco sauce
tacolike
taconic
taconite
taconites
tacops
tacos
tacrine (current term)
tacrines
tacrolimus
tact
tactable
tactful
tactfully
tactfulness
tactfulnesses
tactic
tactical
tactical aeromedical evacuation
tactical aeromedical evacuations
tactical air command centers
tactical air commander

Literary usage of Tacrine

Below you will find example usage of this term as found in modern and/or classical literature:

1. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"Under these circumstances the effects of both nicotine and tacrine were blocked by ... These findings demonstrate that tacrine can both inhibit or enhance ..."

2. Alzheimer's Disease: Diagnosis, Cause & Treatment by Margaret Strock (1996)
"One drug in particular, THA or tacrine (trade name, Cognex), ... tacrine can, however, have side effects, including elevation of liver functioning tests. ..."

3. Guide to Clinical Preventive Services: Report of the U. S. Preventive by DIANE Publishing Company (1996)
"Although several studies reported no benefit,52'53 the three largest trials suggested a significant but modest benefit of tacrine in patients with mild to ..."

4. Value of Psychiatric Treatment: Its Efficacy in Severe Mental Disorders edited by Samuel J. Keith (1996)
"One drug, tacrine, is available in an expanded access program, ... With tacrine and related medications reversible liver tox- icity is a major side effect. ..."

5. Genetics Testing in the New Millennium: Advances, Standards and Implications edited by Constance A. Morella (2001)
"For example, researchers have discovered that Alzheimer's patients with the gene subtype ApoE4 are less likely to benefit from the drug tacrine. ..."

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