Medical Definition of Nonreceptor protein tyrosine kinase
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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