Lexic.us

Definition of Neuroblastoma

1. Noun. Malignant tumor containing embryonic nerve cells; usually metastasizes quickly.

Definition of Neuroblastoma

1. Noun. (oncology) A form of cancer that affects the ganglia in various parts of the body. ¹

¹ Source: wiktionary.com

Definition of Neuroblastoma

1. [n -MATA or -MAS]

Medical Definition of Neuroblastoma

1. Malignant tumour derived from primitive ganglion cells. Mainly a tumour of childhood. Commonest sites are adrenal medulla and retroperitoneal tissue. The cells may partially differentiate into cells having the appearance of immature neurons. The tumour shows a consistent deletion of the 1p36 region which is considered the site of the neuroblastoma I gene. Loss of the 1p36 region also correlates with amplification for the N-myc oncogene, particularly in later stages of the disease. Amplification of N-myc with DNA triploidy is associated with poor survival. Hereditary forms of the condition are rare and in such patients there is no risk for other cancers, which suggests a specificity of the antioncogene for neural tissues. (16 Dec 1997)

Lexicographical Neighbors of Neuroblastoma

Literary usage of Neuroblastoma

Below you will find example usage of this term as found in modern and/or classical literature:

1. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"SY5Y is a sub- clone of the human neuroblastoma SK-N- SH and has neurotoxic ... neuroblastoma cell lines. Cell lines have been established from both mouse ..."

2. Surgical and mechanical treatment of peripheral nerves by Byron Stookey, Gotthelf Carl Huber (1922)
"Mallory stain—neuroblastoma; section through tumor of ulnar nerve showing rosettes, K, and connective tissue ..."

3. The Principles of Pathologic Histology by Frank Burr Mallory (1914)
"In this way the ependymal- lined cavities came to hold masses of fibrous tissues J4. neuroblastoma (NEUROCYTOMA, NEUROMA) Definition. ..."

4. The Principles of Pathologic Histology by Frank Burr Mallory (1914)
"In this way the ependymal- lined cavities came to hold masses of fibrous tissue. J4. neuroblastoma (NEUROCYTOMA, NEUROMA) Definition. ..."

5. Gulf War And Health by Institute of Medicine (2005)
"To study the effects of parental occupational exposure on the incidence of neuroblastoma among children, De Roos et al. (2001) conducted a case-control ..."

6. Differential diagnosis presented through an analysis of 385 [and] 317 cases by Richard Clarke Cabot (1918)
"2785 showed a neuroblastoma of the neck, pleura, liver, retroperitoneal and bronchial lymph-nodes; tuberculosis of a bronchial lymphatic gland, ..."

7. Nervous and Mental Disease Monograph Series (1915)
"Harbitz first considers the third variety, the malignant neuroblastoma. ... Histologically the structure of all the tumors was that of neuroblastoma which ..."

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