Medical Definition of Multiple endocrine neoplasia type 1

1. A rare syndrome characterised by hyperplasia and/or neoplasms of the pituitary, parathyroid glands, and pancreatic islets. Hyperparathyroidism occurs in 90% of the cases and is usually the first manifestation of the syndrome. The most frequent pancreatic manifestation is gastrinoma typically leading to zollinger-ellison syndrome. The appearance of this condition has been limited to the loss of allelic heterozygosity at the 11q13 locus on the long arm of chromosome 11. Patients overall exhibit long survival times. Chemotherapy is rare and surgical management is generally dependent on the genetic expression in individual patients. (12 Dec 1998)

Lexicographical Neighbors of Multiple Endocrine Neoplasia Type 1

multiple birth offspring
multiple carboxylase deficiency
multiple chemical sensitivity
multiple cloning site
multiple correlation
multiple correlation coefficient
multiple drug resistant tuberculosis
multiple ego states
multiple embolism
multiple endocrine adenomatosis
multiple endocrine deficiency syndrome
multiple endocrine neoplasia
multiple endocrine neoplasia 1
multiple endocrine neoplasia 2
multiple endocrine neoplasia 3
multiple endocrine neoplasia type 1 (current term)
multiple endocrine neoplasia type 2
multiple endocrine neoplasia type 2a
multiple epiphysial dysplasia
multiple exostosis
multiple expansion
multiple expansions
multiple exposure
multiple fission
multiple fracture
multiple fruit
multiple fruits
multiple gestation
multiple glandular deficiency syndrome

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