Definition of Missense

1. Noun. (biology) A damaged DNA sequence that is meaningful but has an incorrect meaning, with the result that its products do not do what they are supposed to do. ¹

¹ Source: wiktionary.com

Definition of Missense

1. a form of genetic mutation [n -S]

Medical Definition of Missense

1. As used in genetics, a mutation that causes a sequence such that there is a substitution of one amino acid residue for another. Missense suppression, a mutation in tRNA that allows for incorporation of an amino acid residue that allows for full function of the gene product. (05 Mar 2000)

Lexicographical Neighbors of Missense

misseeming
misseems
misseen
missees
missegregation
missel
missel thrush
misseldine
missels
misseltoe
misseltoes
missemblance
missend
missending
missends
missense (current term)
missense mutation
missense mutations
missenses
missent
misserve
misserved
misserves
misserving
misses
misseses
misset
missets
missetting
missey

Literary usage of Missense

Below you will find example usage of this term as found in modern and/or classical literature:

1. Genomic Signal Processing and Statistics by Edward R Dougherty (2005)
"We found that the probability of a microbial missense mutation causing a ... We tested our model on pathogenic allelic variants (missense mutations or ..."

2. Diabetes in America by Ronald Aubert (1996)
"Stoffel M, Patel P, Lo YM, Hattersley AT, Lucassen AM, Page R, Bell JI, Bell Gl, Turner RC, Wainscoat JS: missense glucokinase mutation in maturity-onsei ..."

3. Biographical Memoirs by National Academy Of Sciences, National Academy of Sciences Staff, Caroline K. McEuen (1980)
"Restriction, de-restriction and mistranslation in missense suppression. Ribosomal discrimination of tRNA's. J. Mol. Biol., 64:119-34. ..."

4. Molecular Neurobiology: Proceedings of the 2nd NIMH Conference by Steven Zalcman (1995)
"... missense mutation was introduced. This corresponding mutation in ras is known to decrease the GTP hydrolysis rate. Both the wild type and mutant forms ..."

5. Novel Systems for the Study of Human Disease: From Basic Research to by OECD Staff, (Paris) Organisation for Economic Co-ope, SourceOECD (Online service) (1998)
"... BJ WAINWRIGHT (1996), “Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype-phenotype correlations”, Embo Journal 15, pp. ..."

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