Medical Definition of Major groove

1. In a detailed analysis of DNA structure, there are two types of grooves that can be seen; the major groove has the nitrogen and oxygen atoms of the base pairs pointing inward toward the helical axis, while in the minor groove, the nitrogen and oxygen atoms point outwards; important because the major groove is more dependent on base composition and may be the site for protein recognition of specific DNA sequences or regions. (05 Mar 2000)

Lexicographical Neighbors of Major Groove

major calices
major chord
major connector
major depression
major depressive episode
major diameter
major diatonic scale
major duodenal papilla
major element
major epilepsy
major fissure
major forceps
major general
major generals
major groove (current term)
major hippocampus
major histocompatabilty complex
major histocompatibility antigen
major histocompatibility complex
major hypnosis
major hysteria
major in
major interval
major intervals
major intrinsic protein
major key
major keys
major league
major leaguer

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