Definition of Lafora's disease
1. Noun. Epilepsy characterized by clonus of muscle groups and progressive mental deterioration and genetic origin.
Medical Definition of Lafora's disease
1. A form of progressive myoclonus epilepsy beginning from age 6 to 19; characterised by generalised tonic-clonic seizures, resting and action myoclonus, ataxia, dementia, and classic EEG findings, including polyspike and wave discharges; basophilic cytoplasmic inclusion bodies present in portions of the brain, the liver, and skin, as well as the duct cells of the sweat glands. Death usually occurs within 10 years of onset; autosomal recessive inheritance. Synonym: Lafora's disease. (05 Mar 2000)
Lafora's Disease Pictures
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