Definition of Hodgkin's disease

1. Noun. A malignant disorder in which there is progressive (but painless) enlargement of lymph tissue followed by enlargement of the spleen and liver.

Generic synonyms: Lymphoma



Definition of Hodgkin's disease

1. Noun. (context oncology disease) The former name of Hodgkin's lymphoma. ¹

¹ Source: wiktionary.com

Medical Definition of Hodgkin's disease

1. A human malgnant disorder of lymph tissue (lymphoma) that appears to originate in a particular lymph node and later spreads to the spleen, liver and bone marrow. It occurs mostly in individuals between the ages of 15 and 35. It is characterised by progressive, painless enlargement of the lymph nodes, spleen and general lymph tissue. Giant cells, the Reed Sternberg cells, with mirror image nuclei are diagnostic. Immunological depletion, caused perhaps by the excessive growth of neoplastic histiocytes, occurs. Four types of the disease are recognised depending on the relative predominance of various neoplastic derivatives of the lymphoid series. Pyrexia is often a feature of the disease. Death often results from generalised immunological inability to respond to infections. If detected early, it has a high remission rate. Staging: Ann Arbor classification; each stage is further classified as:, A no symptoms, B fever, sweats, weight loss. Stage I - involvement of a single lymph-node region or extralymphatic site. Stage II - two or more sites of involvement on the same side of the diaphragm. Stage III - disease involvement on both sides of the diaphragm. Stage IV - disseminated disease of extralymphatic organs, with or without lymph-node involvement. Indicence: approximately 1,500 new cases per year in the UK. (30 Mar 2000)

Hodgkin's Disease Pictures

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Lexicographical Neighbors of Hodgkin's Disease

Hodder
Hoddle
Hodeida
Hoder
Hodge
Hodge's pessary
Hodgen
Hodgen splint
Hodgeon
Hodges
Hodgett
Hodgetts
Hodgin
Hodgins
Hodgkin
Hodgkin's disease
Hodgkin's lymphoma
Hodgkin-Key murmur
Hodgkins
Hodgkinson
Hodgkison
Hodgkiss
Hodgkisson
Hodgskin
Hodgson
Hodkin
Hodkinson
Hodr
Hodson
Hoechst 33258

Literary usage of Hodgkin's disease

Below you will find example usage of this term as found in modern and/or classical literature:

1. Dietetics; Or, Food in Health and Disease by William Tibbles (1914)
"Hodgkin-s Disease ... Mycosis fungoides is said by Ziegler to be a special development of Hodgkin-s disease, and he believes both to be due to a ..."

2. An introduction to pathology and morbid anatomy by Thomas Henry Green (1884)
"HODGKIN S DISEASE. This disease is characterised by the enlargement of the lymphatic glands in various parts of the body, together with the development of ..."

3. The Dublin Journal of Medical Science (1889)
"... to contain tubercles, and the lymphatics were all in a similar condition, and sometimes even caseous and soft. Now, this was not Hodgkin-s disease. ..."

4. A Text-book on Minor Surgery by John Colin Vaughan (1922)
"Enlargement of the cervical lymph nodes occurs as a part of the general glandular swelling in leukemia, in Hodgkin-s disease, and in malignant disease. ..."

5. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1911)
"... AND WS THAYER, MD, PROFESSOR OF CLINICAL MEDICINE, JOHNS HOPKINS UNIVERSITY, BALTIMORE, MARTLAND. The Blood in Hodgkin s Disease.—FABIAN (Wien. klin. ..."

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