Definition of Histamine headache
1. Noun. A painful recurring headache associated with the release of histamine from cells.
Medical Definition of Histamine headache
1. A term used to describe a headache that is typified by constant, unilateral pain around the eye, with onset usually within 2-3 hours of falling asleep. Can be accompanied by a blocked nasal passage, runny nose, and-or tearing. One may also notice facial flushing, ptosis (dropping eyelid), facial swelling and constriction of the pupils. (27 Sep 1997)
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