Medical Definition of Gamma-l-glutamyl-l-cysteinylglycine

1. The tripeptide _ glutamylcysteinylglycine. It contains an unusual peptide linkage between the _ carboxyl group of the glutamate side chain and the amine group of cysteine. The concentration of glutathione in animal cells is _5mM and its sulphydryl group is kept largely in the reduced state. This allows it to act as a sulphydryl buffer, reducing any disulphide bonds formed within cytoplasmic proteins to cysteines. Hence, few, if any, cytoplasmic proteins contain disulphide bonds. Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids and participates in leucotriene synthesis. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Gamma-l-glutamyl-l-cysteinylglycine

gamma-glutamyl cycle
gamma-glutamyl dipeptidase
gamma-glutamyl hydrolase
gamma-glutamyl transpeptidase
gamma-glutamylcyclotransferase
gamma-glutamylcysteine
gamma-glutamylhistamine synthetase
gamma-glutamyltransferase
gamma-guanidinobutyraldehyde dehydrogenase
gamma-hydroxybutyrate
gamma-hydroxybutyric acid
gamma-hydroxybutyric acids
gamma-interferon
gamma-iodopropyleneglycol
gamma-iron
gamma-l-glutamyl-l-cysteinylglycine (current term)
gamma-linolenic acid
gamma-oxalomesaconate hydratase
gamma-ray
gamma-ray burst
gamma-tocopherol
gamma-tocopherol methyltransferase
gamma-tolerance
gamma acid
gamma alcoholism
gamma aminobutyric acid
gamma aminobutyric acid receptor
gamma angle
gamma benzene hexachloride
gamma bomb

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