Definition of Fluorescein

1. Noun. A yellow dye that is visible even when highly diluted; used as an absorption indicator when silver nitrate solution is added to sodium chloride in order to precipitate silver chloride (turns pink when no chloride ions are left in solution and negative fluorescein ions are then absorbed).

Exact synonyms: Fluoresceine, Fluorescent Dye, Resorcinolphthalein
Category relationships: Solution
Generic synonyms: Absorption Indicator, Dye, Dyestuff
Specialized synonyms: Bromeosin, Eosin

Definition of Fluorescein

1. n. A yellowish red, crystalline substance, C20H12O5, produced by heating together phthalic anhydride and resorcin; -- so called, from the very brilliant yellowish green fluorescence of its alkaline solutions. It has acid properties, and its salts of the alkalies are known to the trade under the name of uranin.

Definition of Fluorescein

1. Noun. (chemistry) Any of a class of yellow xanthene dyes which are visible when highly diluted; used forensically to detect traces of blood, and in analytical chemistry as an indicator in silver nitrate titrations ¹

¹ Source: wiktionary.com

Definition of Fluorescein

1. [n -S]

Medical Definition of Fluorescein

1. Fluorophore commonly used in microscopy. Fluorescein di acetate can be used as a vital stain or can be conjugated to proteins (particularly antibodies) using isothiocyanate. Excitation is at 365nm and the emitted light is green yellow (450-490nm). The emission spectrum is pH sensitive and fluorescein can therefore be used to measure pH in intracellular compartments. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Fluorescein

fluorated
fluorcaphite
fluorene
fluorenes
fluorenol
fluorenols
fluorenone
fluorenones
fluorenyl
fluorenylidene
fluorenylidenes
fluorescamine
fluorescamines
fluoresce
fluoresced
fluorescein (current term)
fluorescein-5-isothiocyanate
fluorescein-conjugated antibody
fluorescein angiography
fluorescein eye examination
fluorescein instillation test
fluorescein isocyanate
fluorescein isothiocyanate
fluorescein sodium
fluorescein string test
fluoresceine
fluoresceines
fluoresceins
fluorescence
fluorescence-activated cell sorter

Literary usage of Fluorescein

Below you will find example usage of this term as found in modern and/or classical literature:

1. Allen's Commercial Organic Analysis: A Treatise on the Properties, Modes of by Alfred Henry Allen (1911)
"Substitution derivatives of fluorescein may be obtained by the condensation of ... nitric acid) on fluorescein, or by combining the two processes. ..."

2. Experimental Organic Chemistry by James Flack Norris (1915)
"Preparation of a Phthalein: fluorescein (SECTIONS 543, 545). ... fluorescein can be crystallized by dissolving it in hot alcohol or in hot glacial acetic ..."

3. Synthetic Colouring Matters: Dyestuffs Derived from Pyridine, Quinoline by John Theodore Hewitt (1922)
"As to the constitution of fluorescein, the only question left to consider ... 280); fluorescein furnishes derivatives of both types and at present we shall ..."

4. Synthetic Colouring Matters: Dyestuffs Derived from Pyridine, Quinoline by John Theodore Hewitt (1922)
"Thus bromine reacts with fluorescein to give di- or ... fluorescein derivatives substituted in the phthalic residue are made by condensing the corresponding ..."

5. Allen's Commercial Organic Analysis: A Treatise on the Properties, Modes of by Alfred Henry Allen (1911)
"Substitution derivatives of fluorescein may be obtained by the condensation of ... nitric acid) on fluorescein, or by combining the two processes. ..."

6. Experimental Organic Chemistry by James Flack Norris (1915)
"Preparation of a Phthalein: fluorescein (SECTIONS 543, 545). ... fluorescein can be crystallized by dissolving it in hot alcohol or in hot glacial acetic ..."

7. Synthetic Colouring Matters: Dyestuffs Derived from Pyridine, Quinoline by John Theodore Hewitt (1922)
"As to the constitution of fluorescein, the only question left to consider ... 280); fluorescein furnishes derivatives of both types and at present we shall ..."

8. Synthetic Colouring Matters: Dyestuffs Derived from Pyridine, Quinoline by John Theodore Hewitt (1922)
"Thus bromine reacts with fluorescein to give di- or ... fluorescein derivatives substituted in the phthalic residue are made by condensing the corresponding ..."

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