Definition of Estradiol

1. Noun. The most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer.

Exact synonyms: Oestradiol
Substance meronyms: Loestrin, Lo/ovral, Modicon, Norlestrin, Ovocon, Ovral
Generic synonyms: Estrogen, Oestrogen

Definition of Estradiol

1. Noun. (biochemistry) A potent estrogenic hormone (''(17)-estra-1,3,5-triene-3,17-diol'') produced in the ovaries of all vertebrates; the synthetic compound is used medicinally to treat estrogen deficiency and breast cancer. ¹

¹ Source: wiktionary.com

Definition of Estradiol

1. [n -S]

Medical Definition of Estradiol

1. A hormone (272 D) synthesised mainly in the ovary, but also in the placenta, testis and possibly adrenal cortex. A potent oestrogen. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Estradiol

estoile
estoiles
estop
estoppage
estoppages
estopped
estoppel
estoppel by deed
estoppels
estopping
estops
estover
estovers
estrade
estrades
estradiol (current term)
estradiol-17 beta sulfotransferase
estradiol 15 alpha-hydroxylase
estradiol 16 alpha-hydroxylase
estradiol antagonists
estradiol benzoate unit
estradiol dehydrogenases
estradiol patch
estradiol receptor tyrosine kinase
estradiols
estragole
estragon
estragon oil
estragons
estral

Literary usage of Estradiol

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"As expected, specific estradiol receptors are present in such an ... estradiol receptor activity was reported to rise from Day 4 to a maximum on Day 12 of ..."

2. Molecular Neurobiology: Proceedings of the Second Nimh Conference by Steven Zalcman (1995)
"Hypothalamic slices were prepared from ovariectomized female rats administered oil (OVX) or 2 ug of estradiol benzoate (EB) 24 and 48 hr before sacrifice. ..."

3. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"Moreover, smoking appears to alter the metabolism of estradiol, leading to enhanced formation of the inactive catechol estrogens. (Auth. Abs.) 91-4047. ..."

4. Eighth Annual Report on Carcinogens: 1998 Summary edited by Barry Leonard (1999)
"There is inadequate evidence for the Carcinogenicity of estradiol-17ß in humans ... Studies of humans given estradiol-17ß alone are not available to IARC ..."

5. 6th Annual Report on Carcinogens (1991) by DIANE Publishing Company (1994)
"Subcutaneous implants of estradiol- 17 induced mammary tumors, ... There is inadequate evidence for the carcinogenicity of estradiol-17 in humans ..."

6. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"When measured at hatching, the eggs treated with DDE (or estradiol) were observed to ... estradiol, but not DDE, also increased allantoic estradiol levels. ..."

7. Carcinogenic Potency Database, Endocrine Disruptors edited by Lois Swirsky Gold (2000)
"A small increase in circulating estradiol in male fetuses permanently increases adult ... Specifically, a 50% increase in circulating estradiol led to a 40% ..."

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