Lexic.us

Definition of Electrophoresis

1. Noun. The motion of charged particles in a colloid under the influence of an electric field; particles with a positive charge go to the cathode and negative to the anode.

Definition of Electrophoresis

1. Noun. the migration of electrically charged molecules through a medium under the influence of an electric field ¹

2. Noun. a method for the separation and analysis of large molecules (such as proteins) by migrating a colloidal solution of them through a gel; gel electrophoresis ¹

¹ Source: wiktionary.com

Definition of Electrophoresis

1. [n -RESES]

Medical Definition of Electrophoresis

1. Separation of ionic molecules, (principally proteins) by the differential migration through a gel according to the size and ionic charge of the molecules in an electrical field. High resolution techniques normally use a gel support for the fluid phase. Examples of gels used are starch, acrylamide, agarose or mixtures of acrylamide and agarose. Frictional resistance produced by the support causes size, rather than charge alone, to become the major determinant of separation. Smaller molecules with a more negative charge will travel faster and further through the gel toward the anode of an electrophoretic cell when high voltage is applied. Similar molecules will group on the gel. They may be visualised by staining and quantitated, in relative terms, using densitometers which continuously monitor the photometric density of the resulting stain. The electrolyte may be continuous (a single buffer) or discontinuous, where a sample is stacked by means of a buffer discontinuity, before it enters the running gel/ running buffer. The gel may be a single concentration or gradient in which pore size decreases with migration distance. In SDS gel electrophoresis of proteins or electrophoresis of polynucleotides, mobility depends primarily on size and is used to determined molecular weight. In pulse field electrophoresis, two fields are applied alternately at right angles to each other to minimise diffusion mediated spread of large linear polymers. See: electrofocussing, pulse field electrophoresis (01 Dec 1998)

Lexicographical Neighbors of Electrophoresis

Literary usage of Electrophoresis

Below you will find example usage of this term as found in modern and/or classical literature:

1. Science by American Association for the Advancement of Science (1883)
"... the electrophoresis Computer automatically scans eight electrophoresis separations. There is no need to make tedious adjustments since ..."

2. Molecular Neurobiology: Proceedings of the Second Nimh Conference by Steven Zalcman (1995)
"In our studies, we employ capillary electrophoresis coupled with laser-induced fluorescence detection to resolve questions surrounding differential ..."

3. Journal of the American Chemical Society by American Chemical Society (1915)
"A cell for the observation of electrophoresis was designed, which, on account of its ease of construction and manipulation, warrants description. ..."

4. Proceedings of the Workshop on Long-lived Radionuclide Chemistry in Nuclear by NEA Nuclear Science Committee (1998)
"... Ottawa, Ontario Kl A OH3, Canada Abstract Capillary electrophoresis (CE) is a relatively new technique in the field of metal ion analysis. ..."

5. Mammalian Embryo Genomics by OECD (2003)
"Study of Newly Synthesized Proteins During Bovine Oocyte Maturation In Vitro by Two-Dimensional Gel electrophoresis K. Coenen and MA Sirard Centre de ..."

6. A Handbook of Colloid-chemistry: The Recognition of Colloids, the Theory of by Carl Wilhelm Wolfgang Ostwald, Wolfgang Ostwald, Emil Hatschek (1919)
"electrophoresis.—The sign of the charge of the colloid phase may be determined by noting the direction in which it moves when subjected to the action of an ..."

7. The Neuroscience of Mental Health: A Report on Neuroscience Research edited by Stephen H. Koslow (1997)
"A simulation of the single-cell biosensor/capillary electrophoresis system. ... Capillary electrophoresis Micro-column separation techniques such as ..."

8. Genomic Signal Processing and Statistics by R. Dougherty, Edward R Dougherty (2005)
"For example, both quartz and glass microchips have been fabricated for performing capillary electrophoresis and postcolumn reaction [76] . ..."

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