Definition of Drepanocytic anaemia

1. Noun. A congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape.




Medical Definition of Drepanocytic anaemia

1. Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Drepanocytic Anaemia Pictures

Click the following link to bring up a new window with an automated collection of images related to the term: Drepanocytic Anaemia Images

Lexicographical Neighbors of Drepanocytic Anaemia

drench
drenche
drenched
drenched in
drencher
drenchers
drenches
drenching
drenchingly
drengage
drengages
drent
drepanidium
drepanocyte
drepanocytic
drepanocytic anaemia (current term)
drepanocytic anemia
drere
dreres
dreshel
dreshels
dress'd
dress-down Friday
dress-up party
dress blues
dress circle
dress coat
dress coats
dress code

Other Resources Relating to: Drepanocytic anaemia

Search for Drepanocytic anaemia on Dictionary.com!Search for Drepanocytic anaemia on Thesaurus.com!Search for Drepanocytic anaemia on Google!Search for Drepanocytic anaemia on Wikipedia!

Search