Lexic.us

¹ Source: wiktionary.com

Definition of Busulfan

1. a medicine [n -S]

Medical Definition of Busulfan

1. An alkylating agent having a selective immunosuppressive effect on bone marrow. It has been used in the palliative treatment of chronic myeloid leukaemia, but although symptomatic relief is provided, no permanent remission is brought about. According to the fourth annual report on carcinogens (ntp 85-002, 1985), busulfan is listed as a known carcinogen. Pharmacological action: alkylating agents, antineoplastic agent, alkylating, carcinogens, immunosuppressive agents. Chemical name: 1,4-Butanediol, dimethanesulfonate (12 Dec 1998)

Lexicographical Neighbors of Busulfan

Literary usage of Busulfan

Below you will find example usage of this term as found in modern and/or classical literature:

1. New Developments and Applications in Experimental Design: Selected by William F. Rosenberger, Nancy Flournoy, Weng Kee Wong (1998)
"For example, in cancer chemotherapy, cyclophos- phamide is toxic to the heart and busulfan is toxic to the liver. Therefore, four responses are possible: no ..."

2. Approved Drug Products with Therapeutic Evaluationsby DIANE Publishing Company by DIANE Publishing Company (1995)
"... IN COMBINATION WITH NALOXONE TN= busulfan TN= busulfan TN= BUTYRYLCHOLINESTERASE TN= BUTYRYLCHOLINESTERASE TN= C1-ESTERASE-INHIBITOR, HUMAN, ..."

3. Proceedings of the Society for Experimental Biology and Medicine (1903)
"The second CML patient was studied at primary diagnosis, and the third CML patient was examined during chronic phase while under treatment with busulfan. ..."

4. Leukemia: A Research Report edited by Barry Leonard (1998)
"In many cases, patients who were treated with busulfan alone during the chronic phase are treated with hydroxyurea. Patients who have severe anemia or ..."

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