Definition of Buprenorphine
1. Noun. (medicine) A semisynthetic opioid that is used to treat opioid addiction. ¹
¹ Source: wiktionary.com
Medical Definition of Buprenorphine
1.
17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol. A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Pharmacological action: analgesics, opioid, narcotic antagonists, narcotics.
Chemical name: 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-
(12 Dec 1998)
Lexicographical Neighbors of Buprenorphine
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