Medical Definition of Blast transformation
1.
The morphological and biochemical changes in lymphocytes, both B and T, on exposure to antigen or to a mitogen. The cells appear to move from G0 to G1 stage of the cell cycle. They usually enlarge and proceed to S phase and mitosis later. The process probably involves receptor cross linking on the plasma membrane.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Blast Transformation
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