Definition of Anaphylatoxin

1. Noun. (biochemistry) Any of several toxic substances that trigger anaphylaxis ¹

¹ Source: wiktionary.com

Medical Definition of Anaphylatoxin

1. A substance which stimulates the release of histamine producing an inflammatory reaction as part of an immunological response to a foreign antigen. This can lead to anaphylactic shock. Anaphylatoxin is fragment of complement from C3a, C4a, C5a, and C5a des-arginine produced in the serum during complement activation. These fragments produce smooth muscle contraction, mast cell histamine release, modify platelet aggregation, and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from strongest to weakest is C5a, C3a, C4a, and C5a des-arginine. (22 Feb 2008)

Lexicographical Neighbors of Anaphylatoxin

anaphrodisiacs
anaphylactic
anaphylactic antibody
anaphylactic intoxication
anaphylactic reaction
anaphylactic shock
anaphylactogen
anaphylactogenesis
anaphylactogenic
anaphylactogens
anaphylactoid
anaphylactoid crisis
anaphylactoid purpura
anaphylactoid shock
anaphylatoxin (current term)
anaphylatoxin inactivator
anaphylatoxins
anaphylaxes
anaphylaxis
anaplasia
anaplasias
anaplasic
anaplasma
anaplasmataceae
anaplasmataceae infections
anaplasmoses
anaplasmosis
anaplastic
anaplastic astrocytoma

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