Lexic.us

¹ Source: wiktionary.com

Definition of Acetazolamide

1. [n -S]

Medical Definition of Acetazolamide

1. A carbonic anhydrase inhibitor that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. Pharmacological action: anticonvulsants, carbonic anhydrase inhibitors, diuretics. Chemical name: Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)- (12 Dec 1998)

Lexicographical Neighbors of Acetazolamide

Literary usage of Acetazolamide

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"However, recent reports have suggested that carbonic anhydrase inhibition may have been incomplete at the acetazolamide dosage used. Mathisen, et al. ..."

2. Code of Federal Regulations, Title 21, Food and Drugs, PT. 500-599, Revised by Food and Drug Administration (FDA) Staff (2005)
"The drug is in a powder form containing acetazolamide sodium, USP equivalent to 25 percent acetazolamide activity. (b) Sponsor. See No. ..."

3. Health Information for International Travel edited by Rosamond R. Dewart (1999)
"acetazolamide has been shown, under both simulated and actual climbing conditions, ... acetazolamide should not be taken by individuals who are allergic to ..."

4. Code of Federal Regulations, Title 21, Food and Drugs, PT. 300-499, Revised by Food and Drug Administration (FDA) Staff (2005)
"... of aspirin and acetazolamide can lead to high serum concentrations of acetazolamide (and toxicity) due to competition at the renal tubule for secretion. ..."

5. Health Information for International Travel (1994) by DIANE Publishing Company (1995)
"acetazolamide has been shown, under both simulated and actual climbing conditions, ... acetazolamide should not be taken by individuals who are allergic to ..."

6. Nutrient Composition of Rations for Short-term, High-intensity Combat Operations by Institute of Medicine (U. S.), Fnb, High-stress Situations, Committee on Military Nutrition Research, National Academy of Sciences (2006)
"Randomised, double blind, placebo controlled comparison of Ginkgo biloba and acetazolamide for prevention of acute mountain sickness among Himalayan ..."

7. Guide To Clinical Preventive Services by U. S. Preventive Services Task Force (1989)
"Antiglaucoma medications (eg, timolol, pilocarpine, epinephrine, acetazolamide) must be taken for life and are accompanied by a variety of ocular and ..."

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